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Successful Validation of a New Genetically Engineered Miniature Pig Model
Mattawan, Mich. and Sioux Center, Iowa (Aug. 27, 2015) : MPI Research and Exemplar Genetics today announced the first successful validation of a new genetically engineered miniature pig model, offering an attractive alternative to rodent models, of atherosclerosis. The ExeGen® LDLR miniswine is a pig model in which the LDL receptor (LDLR) gene is knocked out, resulting in a more accurate analogue to atherosclerosis in humans, providing increased value to human clinical trials.
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Exemplar Genetics to Exhibit at AALAS 66th National Meeting November 1–5, 2015
AALAS 66th National Meeting Phoenix, AZ November 1–5, 2015 Phoenix Convention Center Convention website.

Intrexon to Acquire Remaining Stake in Exemplar Genetics
Intrexon Collaborators Obtain Access to Premier Pipeline of Large Animal Research Models and Custom Animal Development
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Ground-breaking Research Made Possible by Exemplar Genetics
The latest disease model from Exemplar Genetics, a company committed to enabling research into life-threatening human diseases, is featured in the current issue of PLOS ONE magazine.
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ExeGen LDLR MiniSwine

Features consistent, stable hypercholesterolemia that can be further modulated by diet. Predictable, progressive atherosclerosis that manifests on an accelerated timeline. Atherosclerotic lesion formation in the aorta and coronary arteries that model key pathophysiological aspects of human atherosclerosis. Defined Yucatan miniature swine genetics that offers greater consistency.

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A rare opportunity arises for an family fighting a rare disease

“You could have picked me up off of the floor.  Out of 50,000 people at a conference, the chances of meeting someone researching A-T is very, very rare. Dr. Swart never could have imagined that I was connected to the organization or a mother of three A-T adults.  I told him that maybe I could help,” Amy said, laughing.

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Discovery drives the human race to new heights each day.

Explorers in all fields have made our lives and world better through their courage to venture into new frontiers and beyond. Yet, their ability to discover has always relied on the proper vehicle to propel them from theory to reality. At Exemplar Genetics, we enable discovery by providing the vehicle to break new ground on the medical research frontier.

Until now, researchers have lacked animal models that faithfully  represent human diseases. As a result, a sizeable barrier has blocked progress in the discovery of human disease mechanisms; novel diagnostics, procedures, devices, prevention strategies and  therapeutics; and the ability to predict in humans the efficacy of those next-generation procedures, devices, and therapeutics.

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